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- Title
The role of proteomics in depression research.
- Authors
Martins-de-Souza, Daniel; Harris, Laura W; Guest, Paul C; Turck, Christoph W; Bahn, Sabine
- Abstract
Depression is a severe neuropsychiatric disorder affecting approximately 10% of the world population. Despite this, the molecular mechanisms underlying the disorder are still not understood. Novel technologies such as proteomic-based platforms are beginning to offer new insights into this devastating illness, beyond those provided by the standard targeted methodologies. Here, we will show the potential of proteome analyses as a tool to elucidate the pathophysiological mechanisms of depression as well as the discovery of potential diagnostic, therapeutic and disease course biomarkers.
- Publication
European archives of psychiatry and clinical neuroscience, 2010, Vol 260, Issue 6, p499
- ISSN
1433-8491
- Publication type
Journal Article
- DOI
10.1007/s00406-009-0093-2