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- Title
Association of the s allele of the 5-HTTLPR with neuroticism-related traits and temperaments in a psychiatrically healthy population.
- Authors
Gonda, Xenia; Fountoulakis, Konstantinos N; Juhasz, Gabriella; Rihmer, Zoltan; Lazary, Judit; Laszik, Andras; Akiskal, Hagop S; Bagdy, Gyorgy
- Abstract
Research concerning the genetic background of traits, temperaments and psychiatric disorders has been rapidly expanding. One of the most frequently studied genetic polymorphisms in the background of psychological and psychiatric phenomena is the 5-HTTLPR polymorphism of the serotonin transporter gene which has earlier been found to be associated with neuroticism and neuroticism-related traits and disorders. However, both the neuroticism trait and psychiatric disorders are complex and composed of several subfacets. The aim of our study was to investigate the association of the 5-HTTLPR polymorphism with several smaller, distinct and better characterisable phenomena related to the neuroticism trait.
- Publication
European archives of psychiatry and clinical neuroscience, 2009, Vol 259, Issue 2, p106
- ISSN
1433-8491
- Publication type
Journal Article
- DOI
10.1007/s00406-008-0842-7