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- Title
Immunohistochemical expression of p16 and HPV L1 capsid proteins as predictive markers in cervical lesions.
- Authors
Izadi-Mood, Narges; Sarmadi, Soheila; Eftekhar, Zahra; Jahanteegh, Hosein-Ali; Sanii, Sanaz
- Abstract
Human papilloma virus (HPV) infection is the most important cause of cervical cancer, but only 2 % of cervical HPV infections will develop into cervical cancer. p16 INK4A has been introduced as a marker for HPV infection in cervix. HPV L1 capsid protein is also known to be associated with the productive phase of HPV infection; however, expression pattern in different HPV-associated cervical lesion and its correlation to p16 expression is not still well understood. The authors aimed to elucidate the relationship between L1 and p16 expression in cervical lesions.
- Publication
Archives of gynecology and obstetrics, 2014, Vol 289, Issue 6, p1287
- ISSN
1432-0711
- Publication type
Journal Article
- DOI
10.1007/s00404-013-3124-1