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- Title
Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction.
- Authors
Frantz, Stefan; Hu, Kai; Adamek, Anna; Wolf, Jürgen; Sallam, Abed; Maier, Sebastian K G; Lonning, Scott; Ling, Hong; Ertl, Georg; Bauersachs, Johann
- Abstract
Transforming growth factor (TGF)-beta is a locally generated cytokine involved in healing processes and tissue fibrosis, all relevant for cardiac remodeling and the development of heart failure after myocardial infarction (MI). However, data regarding the function of TGF-beta after ischemic injury are inconclusive.
- Publication
Basic research in cardiology, 2008, Vol 103, Issue 5, p485
- ISSN
0300-8428
- Publication type
Journal Article
- DOI
10.1007/s00395-008-0739-7