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- Title
Effects of micronutrients on DNA repair.
- Authors
Collins, Andrew R; Azqueta, Amaya; Langie, Sabine A S
- Abstract
DNA repair is an essential cellular function, which, by removing DNA damage before it can cause mutations, contributes crucially to the prevention of cancer. Interest in the influence of micronutrients on DNA repair activity is prompted by the possibility that the protective effects of fruits and vegetables might thus be explained. Two approaches to measuring repair-monitoring cellular removal of DNA damage and incubating cell extract with specifically damaged DNA in an in vitro assay-have been applied in cell culture, whole animal studies, and human trials. In addition, there are numerous investigations at the level of expression of DNA repair-related genes.
- Publication
European journal of nutrition, 2012, Vol 51, Issue 3, p261
- ISSN
1436-6215
- Publication type
Journal Article
- DOI
10.1007/s00394-012-0318-4