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- Title
1,25-Dihydroxyvitamin D and 25-hydroxyvitamin D--mediated regulation of TRPV6 (a putative epithelial calcium channel) mRNA expression in Caco-2 cells.
- Authors
Taparia, Shveta; Fleet, James C; Peng, Ji-Bin; Wang, Xiang Dong; Wood, Richard J
- Abstract
TRPV6 is a member of the vanilloid subfamily of transient receptor potential (TRP) proteins and likely functions as an epithelial calcium channel in calcium-transporting organs, such as the intestine, kidney, and placenta. TRPV6 mRNA expression is strongly regulated by 1,25-dihydroxyvitamin D (1,25VD), the active hormonal form of vitamin D, in intestine and in Caco-2 cells, a human colon cancer cell line.
- Publication
European journal of nutrition, 2006, Vol 45, Issue 4, p196
- ISSN
1436-6207
- Publication type
Journal Article
- DOI
10.1007/s00394-005-0586-3