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- Title
Influence of thymidylate synthase and p53 protein expression on clinical outcome in patients with colorectal cancer.
- Authors
Broll, R; Busch, P; Duchrow, M; Oevermann, E; Schwandner, O; Farke, S; Bruch, H P; Windhövel, U
- Abstract
Thymidylate synthase (TS) and tumor suppressor p53 are two proteins with an influence on tumor resistance to radio-chemotherapy that is well known. For this reason we tested the effect of TS and p53 expression on clinical outcome (tumor recurrence and survival) in patients after curative tumor resection, especially in patients who received adjuvant radio-chemotherapy.
- Publication
International journal of colorectal disease, 2005, Vol 20, Issue 2, p94
- ISSN
0179-1958
- Publication type
Journal Article
- DOI
10.1007/s00384-004-0621-5