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- Title
Estimating the number of coding mutations in genotypic and phenotypic driven N-ethyl-N-nitrosourea (ENU) screens: revisited.
- Authors
Keays, David A; Clark, Taane G; Campbell, Thomas G; Broxholme, John; Valdar, William
- Abstract
We recently described methods for estimating the number of N-ethyl-N-nitrosourea (ENU)-induced coding mutations in phenotypic and genotypic screens. In this article we revisit these methods, clarifying their application. In particular, we focus on the difference between unconditional and conditional probabilities. We also introduce a website to assist investigators in the application of these equations ( http://www.well.ox.ac.uk/enuMutRat ).
- Publication
Mammalian genome : official journal of the International Mammalian Genome Society, 2007, Vol 18, Issue 2, p123
- ISSN
0938-8990
- Publication type
Journal Article
- DOI
10.1007/s00335-006-0065-z