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- Title
A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors.
- Authors
Heath, Elisabeth I; Infante, Jeffrey; Lewis, Lionel D; Luu, Thehang; Stephenson, Joe; Tan, Antoinette R; Kasubhai, Saifuddin; LoRusso, Patricia; Ma, Bo; Suttle, A Benjamin; Kleha, Joseph F; Ball, Howard A; Dar, Mohammed M
- Abstract
As tyrosine kinase inhibitors have been associated with cardiotoxicity, we evaluated the effect of pazopanib, an inhibitor of vascular endothelial growth factor receptor, platelet-derived growth factor receptor, and c-Kit, on electrocardiographic parameters in patients with cancer.
- Publication
Cancer chemotherapy and pharmacology, 2013, Vol 71, Issue 3, p565
- ISSN
1432-0843
- Publication type
Journal Article
- DOI
10.1007/s00280-012-2030-8