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- Title
The minimal impact of food on the pharmacokinetics of ridaforolimus.
- Authors
Stroh, Mark; Li, Xiaodong; Marsilio, Sabrina; Panebianco, Deborah; Johnson-Levonas, Amy; Juan, Axel; Orford, Keith; Agrawal, Nancy; Trucksis, Michele; Wagner, John A; Murphy, Gail; Iwamoto, Marian
- Abstract
Ridaforolimus, a potent inhibitor of the mammalian target of rapamycin (mTOR), is under development for the treatment for solid tumors. This open-label, randomized, 3-period crossover study investigated the effect of food on the pharmacokinetics of ridaforolimus 40 mg as well as safety and tolerability of the study medication.
- Publication
Cancer chemotherapy and pharmacology, 2012, Vol 70, Issue 1, p177
- ISSN
1432-0843
- Publication type
Journal Article
- DOI
10.1007/s00280-012-1897-8