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- Title
Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
- Authors
Prados, Michael D; Yung, W K A; Wen, Patrick Y; Junck, Larry; Cloughesy, Timothy; Fink, Karen; Chang, Susan; Robins, H Ian; Dancey, Janet; Kuhn, John
- Abstract
This is a phase-I study of gefitinib in combination with temozolomide in patients with gliomas. The goal of the study was to define the maximum tolerated dose (MTD) and to characterize the pharmacokinetics of gefitinib when combined with temozolomide.
- Publication
Cancer chemotherapy and pharmacology, 2008, Vol 61, Issue 6, p1059
- ISSN
0344-5704
- Publication type
Journal Article
- DOI
10.1007/s00280-007-0556-y