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- Title
Protection against cisplatin-induced nephrotoxicity by Spirulina in rats.
- Authors
Mohan, Iyyapu Krishna; Khan, Mahmood; Shobha, Jagdish Chandra; Naidu, Madireddy Umamaheswara Rao; Prayag, Aruna; Kuppusamy, Periannan; Kutala, Vijay Kumar
- Abstract
Cisplatin (CP)-induced nephrotoxicity is associated with the increased generation of reactive oxygen metabolites and lipid peroxidation in kidney, caused by the decreased levels of antioxidants and antioxidant enzymes. The purpose of this study was to evaluate the role of Spirulina, blue-green alga with antioxidant properties, in the protection of cisplatin-induced nephrotoxicity in rat.
- Publication
Cancer chemotherapy and pharmacology, 2006, Vol 58, Issue 6, p802
- ISSN
0344-5704
- Publication type
Journal Article
- DOI
10.1007/s00280-006-0231-8