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- Title
Phase I and pharmacokinetic study of the novel redox-active agent, motexafin gadolinium, with concurrent radiation therapy in patients with locally advanced pancreatic or biliary cancers.
- Authors
Ramanathan, Ramesh K; Fakih, Marwan; Mani, Sridhar; Deutsch, Melvin; Perez, Raymond P; Ritter, Mark A; Eiseman, Julie L; Ivy, S Percy; Trump, Donald L; Belani, Chandra P; Parise, Robert A; Potter, Douglas M; Egorin, Merrill J
- Abstract
To determine the maximum tolerated dose and dose-limiting toxicity (DLT) of the novel anticancer agent, motexafin gadolinium (MGd), administered concurrently with radiation therapy (RT) in patients with locally advanced pancreatic or biliary tumors. The pharmacokinetics of MGd were also evaluated.
- Publication
Cancer chemotherapy and pharmacology, 2006, Vol 57, Issue 4, p465
- ISSN
0344-5704
- Publication type
Journal Article
- DOI
10.1007/s00280-005-0071-y