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- Title
A phase II and pharmacokinetic study of pegylated liposomal doxorubicin in patients with advanced hepatocellular carcinoma.
- Authors
Hong, Ruey-Long; Tseng, Yun-Long
- Abstract
Chemotherapy of advanced hepatocellular carcinoma (HCC) is frequently limited by unacceptable toxicity. Long-circulating polyethylene glycol-coated (PEGylated) liposomal doxorubicin (PLD) has low systemic toxicity. Its safety and efficacy in patients with advanced HCC and the relationship between hepatic function and pharmacokinetics were investigated in this phase II study.
- Publication
Cancer chemotherapy and pharmacology, 2003, Vol 51, Issue 5, p433
- ISSN
0344-5704
- Publication type
Journal Article
- DOI
10.1007/s00280-003-0583-2