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- Title
Arterial embolization of unresectable hepatocellular carcinoma with use of microspheres, lipiodol, and cyanoacrylate.
- Authors
Rand, Thomas; Loewe, Christian; Schoder, Maria; Schmook, Maria Theresa; Peck-Radosavljevic, Markus; Kettenbach, Joachim; Wolf, Florian; Schneider, Barbara; Lammer, Johannes
- Abstract
We performed a retrospective analysis of 46 patients with histologically confirmed hepatocellular carcinoma (HCC) who were treated with transarterial embolization (TAE) of the hepatic arteries. To induce permanent embolization, microspheres (Embosphere; 100 to 700 micron) and a mixture of ethiodized oil (Lipiodol Ultrafluide) with cyanoacrylate (Glubran) was injected. A total of 106 TAE procedures were performed. Cumulative survival rates were calculated. No patient died during embolization or within the first 24 hours. Severe procedure-related complications were observed in 2 patients. At the time of analysis, 38 of 46 patients were alive. The 180-, 360-, 520-, and 700-day cumulative survival rates for the total study population were 80.6%, 70.7%, 70.7%, and 47.1%, respectively, with a median survival of 666 days. TAE with the use of microspheres and Lipiodol and cyanoacrylate for unresectable HCC is a feasible treatment modality. Bland embolization with the use of microspheres can be used in patients for whom chemoembolization is not desired.
- Publication
Cardiovascular and interventional radiology, 2005, Vol 28, Issue 3, p313
- ISSN
0174-1551
- Publication type
Journal Article
- DOI
10.1007/s00270-004-0153-y