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- Title
Molecular testing for somatic mutations improves the accuracy of thyroid fine-needle aspiration biopsy.
- Authors
Moses, Willieford; Weng, Julie; Sansano, Ileana; Peng, Miao; Khanafshar, Elham; Ljung, Britt-Marie; Duh, Quan-Yang; Clark, Orlo H; Kebebew, Electron
- Abstract
Thyroid fine-needle aspiration (FNA) biopsy is indeterminate or suspicious in up to 30% of cases and these patients are commonly subjected to at least a diagnostic hemithyroidectomy. If malignant on histology, a completion thyroidectomy is usually performed, which may be associated with higher morbidity. To determine the clinical utility of genetic testing in thyroid FNA biopsy, we conducted a prospective clinical trial.
- Publication
World journal of surgery, 2010, Vol 34, Issue 11, p2589
- ISSN
1432-2323
- Publication type
Journal Article
- DOI
10.1007/s00268-010-0720-0