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- Title
Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury.
- Authors
Figueiredo, Jose-Luiz; Siegel, Cory; Nahrendorf, Matthias; Weissleder, Ralph
- Abstract
Accidental injury to the common bile duct is a rare but serious complication of laparoscopic cholecystectomy. Accurate visualization of the biliary ducts may prevent injury or allow its early detection. Conventional X-ray cholangiography is often used and can mitigate the severity of injury when correctly interpreted. However, it may be useful to have an imaging method that could provide real-time extrahepatic bile duct visualization without changing the field of view from the laparoscope. The purpose of the present study was to test a new near-infrared (NIR) fluorescent agent that is rapidly excreted via the biliary route in preclinical models to evaluate intraoperative real-time near infrared fluorescent cholangiography (NIRFC).
- Publication
World journal of surgery, 2010, Vol 34, Issue 2, p336
- ISSN
1432-2323
- Publication type
Journal Article
- DOI
10.1007/s00268-009-0332-8