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- Title
Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen.
- Authors
Firpo, Matthew A; Gay, David Z; Granger, Steven R; Scaife, Courtney L; DiSario, James A; Boucher, Kenneth M; Mulvihill, Sean J
- Abstract
Timely, accurate diagnosis of pancreatic adenocarcinoma (PA) is hampered by the lack of effective circulating biomarkers. No single test has emerged that improves upon the commonly used biomarker cancer antigen 19-9 (CA 19-9) to discriminate PA from benign conditions effectively. The goals of this study were to validate two acute-phase proteins, haptoglobin and serum amyloid A (SAA), as biomarkers for PA and determine if the combination of haptoglobin, SAA, and CA 19-9 would improve PA diagnosis over CA 19-9 alone.
- Publication
World journal of surgery, 2009, Vol 33, Issue 4, p716
- ISSN
0364-2313
- Publication type
Journal Article
- DOI
10.1007/s00268-008-9853-9