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- Title
Pilot study of mutant ras peptide-based vaccine as an adjuvant treatment in pancreatic and colorectal cancers.
- Authors
Toubaji, Antoun; Achtar, Moujahed; Provenzano, Maurizio; Herrin, Vincent E; Behrens, Robert; Hamilton, Michael; Bernstein, Sarah; Venzon, David; Gause, Barry; Marincola, Francesco; Khleif, Samir N
- Abstract
There is mounting evidence describing the immunosuppressive role of bulky metastatic disease, thus countering the therapeutic effects of tumor vaccine. Therefore, adjuvant immunotherapy may have a better impact on clinical outcome. In this phase II clinical trial, we aimed to test the feasibility of using a specific mutant ras peptide vaccine as an adjuvant immunotherapy in pancreatic and colorectal cancer patients.
- Publication
Cancer immunology, immunotherapy : CII, 2008, Vol 57, Issue 9, p1413
- ISSN
0340-7004
- Publication type
Journal Article
- DOI
10.1007/s00262-008-0477-6