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- Title
Fast and repetitive in-capillary production of [18F]FDG.
- Authors
Wester, Hans-Jürgen; Schoultz, Bent Wilhelm; Hultsch, Christina; Henriksen, Gjermund
- Abstract
The increasing demand for radiopharmaceuticals to be provided reproducibly and flexibly with high frequency for clinical application and animal imaging would be better met by improved or even new strategies for automated tracer production. Radiosynthesis in microfluidic systems, i.e. narrow tubing with a diameter of approximately 50-500 microm, holds promise for providing the means for repetitive multidose and multitracer production. In this study, the performance of a conceptually simple microfluidic device integrated into a fully automated synthesis procedure for in-capillary radiosynthesis (ICR) of clinical grade [(18)F]FDG was evaluated.
- Publication
European journal of nuclear medicine and molecular imaging, 2009, Vol 36, Issue 4, p653
- ISSN
1619-7089
- Publication type
Journal Article
- DOI
10.1007/s00259-008-0985-9