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- Title
Recombinant carcinoembryonic antigen as a reporter gene for molecular imaging.
- Authors
Kenanova, Vania; Barat, Bhaswati; Olafsen, Tove; Chatziioannou, Arion; Herschman, Harvey R; Braun, Jonathan; Wu, Anna M
- Abstract
Reporter genes can provide a way of noninvasively assessing gene activity in vivo. However, current reporter gene strategies may be limited by the immunogenicity of foreign reporter proteins, endogenous expression, or unwanted biological activity. We have developed a reporter gene based on carcinoembryonic antigen (CEA), a human protein with limited normal tissue expression.
- Publication
European journal of nuclear medicine and molecular imaging, 2009, Vol 36, Issue 1, p104
- ISSN
1619-7089
- Publication type
Journal Article
- DOI
10.1007/s00259-008-0921-z