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- Title
A stable neurotensin-based radiopharmaceutical for targeted imaging and therapy of neurotensin receptor-positive tumours.
- Authors
García-Garayoa, Elisa; Bläuenstein, Peter; Blanc, Alain; Maes, Veronique; Tourwé, Dirk; Schubiger, P August
- Abstract
Neurotensin (NT) and its high affinity receptor (NTR1) are involved in several neoplastic processes. Thus, NT-based radiopharmaceuticals are potential tracers for targeted diagnosis and therapy of NTR-positive tumours. A new analogue based on NT(8-13), NT-XIX, with the three enzymatic cleavage sites stabilised, was synthesised and tested.
- Publication
European journal of nuclear medicine and molecular imaging, 2009, Vol 36, Issue 1, p37
- ISSN
1619-7089
- Publication type
Journal Article
- DOI
10.1007/s00259-008-0894-y