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- Title
In vivo imaging of axonal transport using MRI: aging and Alzheimer's disease.
- Authors
Minoshima, Satoshi; Cross, Donna
- Abstract
MRI using manganese as a trans-synaptic axonal tracing agent can unveil dynamics of axonal transport in living subjects. We use this technology to test the hypotheses if impaired axonal transport is a significant pathophysiological process in aging and early Alzheimer's disease (AD) and in part accounting for "selective vulnerability" of projection neurons in AD.
- Publication
European journal of nuclear medicine and molecular imaging, 2008, Vol 35 Suppl 1, pS89
- ISSN
1619-7070
- Publication type
Journal Article
- DOI
10.1007/s00259-007-0707-8