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Title
Rifampicin seems to act as both an inducer and an inhibitor of the metabolism of repaglinide.
Authors
Bidstrup, Tanja Busk; Stilling, Nicolaj; Damkier, Per; Scharling, Birgitte; Thomsen, Mikael Søndergård; Brøsen, Kim
Abstract
To investigate if rifampicin is both an inducer and an inhibitor of repaglinide metabolism, it was determined whether the timing of rifampicin co-administration influences the pharmacokinetics of repaglinide.
Publication
European journal of clinical pharmacology, 2004, Vol 60, Issue 2, p109