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- Title
Anxiety-like behavior of mice produced by conditional central expression of the HIV-1 regulatory protein, Tat.
- Authors
Paris, Jason J; Singh, Harminder D; Ganno, Michelle L; Jackson, Pauline; McLaughlin, Jay P
- Abstract
Human immunodeficiency virus (HIV) infection is associated with substantial increases in generalized anxiety. The HIV regulatory protein, transactivator of transcription (Tat), has been implicated in the neuropathogenesis related to HIV-1 infection. However, direct examination of the effect of Tat on behavioral measures of anxiety has not been demonstrated.
- Publication
Psychopharmacology, 2014, Vol 231, Issue 11, p2349
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-013-3385-1