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- Title
Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold?
- Authors
Remington, Gary; Agid, Ofer; Foussias, George; Ferguson, Larissa; McDonald, Krysta; Powell, Valerie
- Abstract
Clozapine levels are advocated in the monitoring of patients on this drug and have now been used for a number of years. A safety-related threshold has also been proposed, as well as therapeutic lower and upper thresholds. While there has been reasonable consensus regarding a lower therapeutic threshold, this is not the case for the upper thresholds.
- Publication
Psychopharmacology, 2013, Vol 225, Issue 3, p505
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-012-2922-7