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- Title
Effect of D-amphetamine on emotion-potentiated startle in healthy humans: implications for psychopathy and antisocial behaviour.
- Authors
Corr, Philip J; Kumari, Veena
- Abstract
An emerging literature associates increased dopaminergic neurotransmission with altered brain response to aversive stimuli in humans. The direction of the effect of dopamine on aversive motivation, however, remains unclear, with some studies reporting increased and others decreased amygdala activation to aversive stimuli following the administration of dopamine agonists. Potentiation of the startle response by aversive foreground stimuli provides an objective and directional measure of emotional reactivity and is considered useful as an index of the emotional effects of different drugs.
- Publication
Psychopharmacology, 2013, Vol 225, Issue 2, p373
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-012-2824-8