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- Title
Comparison of single-dose and extended methamphetamine administration on reversal learning in rats.
- Authors
Kosheleff, Alisa R; Rodriguez, Danilo; O'Dell, Steve J; Marshall, John F; Izquierdo, Alicia
- Abstract
Protracted use of methamphetamine (mAMPH) can result in long-term impairments in cognitive function in humans. A previous study reported reversal-specific learning impairments in rats after a binge administration of mAMPH. Several studies show that extended exposure to mAMPH may confer protection against cognitive impairments and the insult to monoamine systems typically observed after larger binge doses.
- Publication
Psychopharmacology, 2012, Vol 224, Issue 3, p459
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-012-2774-1