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- Title
Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice.
- Authors
Pastor, Raúl; Reed, Cheryl; Burkhart-Kasch, Sue; Li, Na; Sharpe, Amanda L; Coste, Sarah C; Stenzel-Poore, Mary P; Phillips, Tamara J
- Abstract
Exposure to stressors promotes ethanol (EtOH) consumption and enhances drug craving during abstinence. Corticotropin-releasing factor (CRF), and in particular, CRF actions via type 1 CRF receptors (CRF(1)) are critical in behavioral responses to stressors. CRF(1) play a role in EtOH-induced behavioral neuroadaptation, in binge-like EtOH consumption, and in heightened EtOH consumption in dependent animals.
- Publication
Psychopharmacology, 2011, Vol 218, Issue 1, p169
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-011-2284-6