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- Title
Event related potential (ERP) evidence for selective impairment of verbal recollection in abstinent recreational methylenedioxymethamphetamine ("Ecstasy")/polydrug users.
- Authors
Burgess, Adrian P; Venables, Louise; Jones, Helena; Edwards, Rhiannon; Parrott, Andrew C
- Abstract
Ecstasy is a recreational drug whose active ingredient, 3,4-methylenedioxymethamphetamine (MDMA), acts predominantly on the serotonergic system. Although MDMA is known to be neurotoxic in animals, the long-term effects of recreational Ecstasy use in humans remain controversial but one commonly reported consequence is mild cognitive impairment particularly affecting verbal episodic memory. Although event-related potentials (ERPs) have made significant contributions to our understanding of human memory processes, until now they have not been applied to study the long-term effects of Ecstasy. The aim of this study was to examine the effects of past Ecstasy use on recognition memory for both verbal and non-verbal stimuli using ERPs.
- Publication
Psychopharmacology, 2011, Vol 216, Issue 4, p545
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-011-2249-9