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Title
Characterization of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior.
Authors
Bleickardt, C J; Mullins, D E; Macsweeney, C P; Werner, B J; Pond, A J; Guzzi, M F; Martin, F D C; Varty, G B; Hodgson, R A
Abstract
Vasopressin (AVP) plays a role in regulating anxiety, which is thought to be partially mediated through the V1a receptor. Recently, JNJ-17308616 was identified as a V1a antagonist.