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Title
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
Authors
Fox, Meredith A; Jensen, Catherine L; French, Helen T; Stein, Alison R; Huang, Su-Jan; Tolliver, Teresa J; Murphy, Dennis L
Abstract
Serotonin transporter (SERT) knockout (-/-) mice have an altered phenotype in adulthood, including high baseline anxiety and depressive-like behaviors, associated with increased baseline extracellular serotonin levels throughout life.