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- Title
Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat--a back translational study.
- Authors
Goetghebeur, Pascal; Dias, Rebecca
- Abstract
Selective cognitive impairments, including those of executive function as assessed using the Wisconsin Card Sort Test or intradimensional-extradimensional (ID-ED) tests, are a key feature of schizophrenia but remain inadequately treated by existing therapies. Recently, however, modafinil has been shown to improve attentional set-shifting performance in patients with schizophrenia.
- Publication
Psychopharmacology, 2009, Vol 202, Issue 1-3, p287
- ISSN
1432-2072
- Publication type
Journal Article
- DOI
10.1007/s00213-008-1132-9