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- Title
Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study.
- Authors
Yucel, Kaan; McKinnon, Margaret C; Taylor, Valerie H; Macdonald, Kathryn; Alda, Martin; Young, L Trevor; MacQueen, Glenda M
- Abstract
The majority of volumetric magnetic resonance imaging (MRI) studies of the hippocampus in patients with bipolar disorder (BD) show no differences in hippocampal volume between patients and healthy controls. Significant variability, however, exists in the medication status of patients included in these studies. In particular, treatment with lithium may exert long-term effects on hippocampal volume, influencing cognitive outcomes in BD patients.
- Publication
Psychopharmacology, 2007, Vol 195, Issue 3, p357
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-007-0906-9