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- Title
Association of OPRM1 A118G variant with the relative reinforcing value of nicotine.
- Authors
Ray, R; Jepson, C; Patterson, F; Strasser, A; Rukstalis, M; Perkins, K; Lynch, K G; O'Malley, S; Berrettini, W H; Lerman, C
- Abstract
The endogenous opioid system has been implicated in substance abuse and response to pharmacotherapies for nicotine and alcohol addiction. We examined (1) the association of the functional OPRM1 A118G variant with the relative reinforcing value of nicotine and (2) the main and interacting effects of the mu-opioid receptor antagonist naltrexone on nicotine reinforcement.
- Publication
Psychopharmacology, 2006, Vol 188, Issue 3, p355
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-006-0504-2