We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Guidelines on nicotine dose selection for in vivo research.
- Authors
Matta, Shannon G; Balfour, David J; Benowitz, Neal L; Boyd, R Thomas; Buccafusco, Jerry J; Caggiula, Anthony R; Craig, Caroline R; Collins, Allan C; Damaj, M Imad; Donny, Eric C; Gardiner, Phillip S; Grady, Sharon R; Heberlein, Ulrike; Leonard, Sherry S; Levin, Edward D; Lukas, Ronald J; Markou, Athina; Marks, Michael J; McCallum, Sarah E; Parameswaran, Neeraja; Perkins, Kenneth A; Picciotto, Marina R; Quik, Maryka; Rose, Jed E; Rothenfluh, Adrian; Schafer, William R; Stolerman, Ian P; Tyndale, Rachel F; Wehner, Jeanne M; Zirger, Jeffrey M
- Abstract
This review provides insight for the judicious selection of nicotine dose ranges and routes of administration for in vivo studies. The literature is replete with reports in which a dosaging regimen chosen for a specific nicotine-mediated response was suboptimal for the species used. In many cases, such discrepancies could be attributed to the complex variables comprising species-specific in vivo responses to acute or chronic nicotine exposure.
- Publication
Psychopharmacology, 2007, Vol 190, Issue 3, p269
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-006-0441-0