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- Title
Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers.
- Authors
Johanson, Chris-Ellyn; Frey, Kirk A; Lundahl, Leslie H; Keenan, Pamela; Lockhart, Nancy; Roll, John; Galloway, Gantt P; Koeppe, Robert A; Kilbourn, Michael R; Robbins, Trevor; Schuster, Charles R
- Abstract
Preclinical investigations have established that methamphetamine (MA) produces long-term changes in dopamine (DA) neurons in the striatum. Human studies have suggested similar effects and correlated motor and cognitive deficits. The present study was designed to further our understanding of changes in brain function in humans that might result from chronic high dose use of MA after at least 3 months of abstinence.
- Publication
Psychopharmacology, 2006, Vol 185, Issue 3, p327
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-006-0330-6