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- Title
Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.
- Authors
Lipina, Tatiana; Labrie, Viviane; Weiner, Ina; Roder, John
- Abstract
Schizophrenia is characterized by disturbances in sensorimotor gating and attentional processes, which can be measured by prepulse inhibition (PPI) and latent inhibition (LI), respectively. Research has implicated dysfunction of neurotransmission at the NMDA-type glutamate receptor in this disorder.
- Publication
Psychopharmacology, 2005, Vol 179, Issue 1, p54
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-005-2210-x