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Title
In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders.
Authors
Alt, Andrew; Weiss, Brianne; Ogden, Ann Marie; Li, Xia; Gleason, Scott D; Calligaro, David O; Bleakman, David; Witkin, Jeffrey M
Abstract
Although convergent evidence exists for a role of glutamate in the regulation of anxiety, the involvement of specific glutamate receptor subtypes has yet to be defined.