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- Title
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes.
- Authors
George, Olivier; Vallée, Monique; Le Moal, Michel; Mayo, Willy
- Abstract
The neurosteroids pregnenolone sulfate (PREGS), dehydroepiandrosterone sulfate (DHEAS) and allopregnanolone (3alpha,5alpha THPROG) have been implicated as powerful modulators of memory processes and sleep states in young and aged subjects with memory impairment. As these processes depend on the integrity of cholinergic systems, a specific effect of neurosteroids on these systems may account for their effects on sleep and memory.
- Publication
Psychopharmacology, 2006, Vol 186, Issue 3, p402
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-005-0254-6