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- Title
Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice.
- Authors
Batista, Luciano C; Prediger, Rui D S; Morato, Gina S; Takahashi, Reinaldo N
- Abstract
Several reports have suggested the involvement of brain adenosine and dopamine receptors in different actions produced by ethanol such as motor incoordination or anxiolytic, hypnotic and reinforcing effects. The co-localization and interaction between adenosine and dopamine receptors in different brain regions has also been well documented. However, few studies have demonstrated the involvement of these mechanisms in the tolerance induced by ethanol.
- Publication
Psychopharmacology, 2005, Vol 181, Issue 4, p714
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-005-0014-7