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- Title
Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia.
- Authors
Egerton, Alice; Reid, Lee; McKerchar, Clare E; Morris, Brian J; Pratt, Judith A
- Abstract
Impaired ability to shift perceptual attentional set forms a core feature of schizophrenic illness and is associated with prefrontal cortical dysfunction. A pharmacological model producing equivalent deficits in rodents may enable the development of novel therapeutic strategies for effective treatment of cognitive impairments in schizophrenia.
- Publication
Psychopharmacology, 2005, Vol 179, Issue 1, p77
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-004-2109-y