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- Title
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma.
- Authors
Volkow, Nora D; Wang, Gene-Jack; Fowler, Joanna S; Molina, Patricia E; Logan, Jean; Gatley, S John; Gifford, Andrew; Ding, Yu-Shin; Wong, Christopher; Pappas, Naomi R; Zhu, Wei; Swanson, James M
- Abstract
The cardiovascular effects of psychostimulant drugs (methylphenidate, amphetamine, cocaine) have been mostly associated with their noradrenergic effects. However, there is some evidence that dopaminergic effects are involved in the cardiovascular actions of these drugs. Here, we evaluated this association in humans.
- Publication
Psychopharmacology, 2003, Vol 166, Issue 3, p264
- ISSN
0033-3158
- Publication type
Journal Article
- DOI
10.1007/s00213-002-1340-7