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- Title
Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis.
- Authors
Valdes, A M; Richards, J B; Gardner, J P; Swaminathan, R; Kimura, M; Xiaobin, L; Aviv, A; Spector, T D
- Abstract
Telomere length decreases with age and is associated with osteoblast senescence. In 2,150 unselected women, leukocyte telomere length was significantly correlated with bone mineral density. Clinical osteoporosis was associated with shorter telomeres, suggesting that telomere length can be used as a marker of bone aging.
- Publication
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007, Vol 18, Issue 9, p1203
- ISSN
0937-941X
- Publication type
Journal Article
- DOI
10.1007/s00198-007-0357-5