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- Title
Positive effect of alendronate on bone mineral density and markers of bone turnover in patients with rheumatoid arthritis on chronic treatment with low-dose prednisone: a randomized, double-blind, placebo-controlled trial.
- Authors
Lems, W F; Lodder, M C; Lips, P; Bijlsma, J W J; Geusens, P; Schrameijer, N; van de Ven, C M; Dijkmans, B A C
- Abstract
Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of patients with the same underlying diseases who receive chronic low-dose prednisone treatment. The objective of the investigation reported here was, therefore, to study the effect of alendronate on bone mineral density (BMD) of the lumbar spine and hips in patients with rheumatoid arthritis (RA) who are on chronic low-dose prednisone treatment.
- Publication
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006, Vol 17, Issue 5, p716
- ISSN
0937-941X
- Publication type
Journal Article
- DOI
10.1007/s00198-005-0037-2