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- Title
Changes in the RANK ligand/osteoprotegerin system are correlated to changes in bone mineral density in bisphosphonate-treated osteoporotic patients.
- Authors
Dobnig, H; Hofbauer, L C; Viereck, V; Obermayer-Pietsch, B; Fahrleitner-Pammer, A
- Abstract
Since the soluble receptor activator of the NF-kappaB ligand (sRANKL) as well as the endogenous anti-resorptive cytokine osteoprotegerin (OPG) are produced by osteoblasts and given that these cells undergo significant changes during antiresorptive treatment, we hypothesized that treatment with bisphosphonates (BP) would be accompanied by changes in serum OPG and sRANKL levels.
- Publication
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006, Vol 17, Issue 5, p693
- ISSN
0937-941X
- Publication type
Journal Article
- DOI
10.1007/s00198-005-0035-4