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- Title
VEGF receptor mRNA expression by ACL fibroblasts is associated with functional healing of the ACL.
- Authors
Vavken, Patrick; Saad, Fawzy A; Fleming, Braden C; Murray, Martha M
- Abstract
Recent advances in the treatment of ACL ruptures employ platelet-rich plasma combined with collagen to modulate growth factor release from platelets to stimulate healing. Among the most notable of these growth factors is VEGF, which is a potent mitogen and stimulator of vascular growth and healing. However, the effect of such a growth factor on healing depends on the cellular ability to bind with its receptor. The purpose of this study was to test (1) whether the strength of a tissue-engineered ACL repair is associated with VEGF receptors' mRNA expression of ACL cells and (2) whether age influences this association.
- Publication
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2011, Vol 19, Issue 10, p1675
- ISSN
1433-7347
- Publication type
Journal Article
- DOI
10.1007/s00167-011-1443-y