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- Title
The effect of etomidate on adrenal function in critical illness: a systematic review.
- Authors
Albert, Stewart G; Ariyan, Srividya; Rather, Ayesha
- Abstract
Although etomidate is a preferred anesthetic agent for rapid sequence intubation (RSI) in critical illness, as an inhibitor of cortisol synthesis (11β-hydroxylase), it may be associated with adrenal dysfunction. The objectives are to review the effects of etomidate versus comparator anesthetics in critical illness for: primary outcome of mortality and secondary outcome of adrenal insufficiency (AI).
- Publication
Intensive care medicine, 2011, Vol 37, Issue 6, p901
- ISSN
1432-1238
- Publication type
Journal Article
- DOI
10.1007/s00134-011-2160-1