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- Title
Advances in mechanisms of repair and remodelling in acute lung injury.
- Authors
Dos Santos, Claudia C
- Abstract
Acute respiratory distress syndrome (ARDS) is the most severe manifestation of acute lung injury (ALI). In patients who survive the acute injury the process of repair and remodelling may be an independent risk factor determining morbidity and mortality. This review explores recent advances in the field of fibroproliferative ARDS/ALI, with a special emphasis on (a) the primary contributing factors with a focus on cellular and soluble factors, and (b) mechanisms involved in repair and remodelling as they pertain to the importance of cell death, re-population, and matrix deposition.
- Publication
Intensive care medicine, 2008, Vol 34, Issue 4, p619
- ISSN
0342-4642
- Publication type
Journal Article
- DOI
10.1007/s00134-007-0963-x