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- Title
Mutagenicity and Genotoxicity in Gill Erythrocyte Cells of Poecilia reticulata Exposed to a Glyphosate Formulation.
- Authors
Souza Filho, José; Sousa, Caio; Da Silva, Cláudio; Sabóia-Morais, Simone; Grisolia, Cesar
- Abstract
Poecilia reticulata were exposed to herbicide Roundup Transorb for micronucleus test, nuclear abnormalities and comet assay. The exposure-concentrations were based on CL following 0, 1.41, 2.83, 4.24 and 5.65 μL L for 24 h. Micronucleus and comets were significantly increased in the gill erythrocyte cells after herbicide exposure compared with the non-exposed group. Results showed a gradual increase in the number of damaged cells, indicating a concentration-dependent effect and that this herbicide was mutagenic and genotoxic to P. reticulata and this effect could be attributed to a combination of compounds contained in the formulation with the active ingredient glyphosate.
- Publication
Bulletin of Environmental Contamination & Toxicology, 2013, Vol 91, Issue 5, p583
- ISSN
0007-4861
- Publication type
Academic Journal
- DOI
10.1007/s00128-013-1103-7